Doing away with the dentist’s drill by helping teeth regenerate themselves

When GlaxoSmithKline bought out NovaMin in 2009, its Oravive with 5% NovaMin touthpaste was discontinued, now its being brought back under GSK's Sensodyne brand.

"Sensodyne Repair & Protect" formulation will launch in over 50 European and International markets during 2011, is the first everyday fluoride toothpaste to contain patented NovaMin® technology, which is scientifically proven to repair* sensitive teeth by forming a tooth-like layer over exposed dentine to help continually repair and protect sensitive areas.

396 Remineralizing Effects of a Bioactive Toothpaste
N.K. SARKAR1, J. CHEUK1, R. SCHAFER1, K. LUONG1, and A. FALSTER2, 1Louisiana State University School of Dentistry, New Orleans, LA, 2Earth and Environmental Sciences, University of New Orleans, New Orleans, LA
Aim: The aim was to study in vitro the efficacy of a bioactive toothpaste, Oravive (Oravive, Fl), in remineralizing decalcified dentin and enamel.
Methods: Transverse sections from the coronal portions of extracted human molars (n=3) were final ground with 1200 grit SiC paper. For surface decalcification, the sections were etched with a 32% phosphoric acid gel and rinsed with water. Two etched sections were brushed for 1 min twice a day using Oravive toothpaste and a manual soft bristle toothbrush and rinsed with water. In between brushing, the sections were stored in a phosphate buffer saline (PBS) solution (pH = 7.2) at 37oC. The solution was replaced every day. After brushing for 10 d, the sections were cleaned ultrasonically in water, dried at 37oC, and examined by SEM and EDXA. The unbrushed etch section served as control.
Results: Toothbrushed samples displayed 1) build up of a reaction layer covering the porous enamel prisms. Degree of coverage varied from place to place; 2) closure of open tubules, partially or completely, with reaction products growing from the peritubular dentinal area; and 3) infiltration of the intertubular matrix with numerous tiny (< 1µ) globules. All reaction products were similar chemically and contained mainly Ca, P, and O with small amounts (<2 wt%) of Na, Mg and Si. Presumably they are an HA-type mineral. Their formation is attributed to a dissolution-precipitation reaction involving Novamin, the bioactive calcium sodium silicophosphate component, of the paste.
Conclusion: Oravive is highly effective in rebuilding demineralized dentin and enamel structures.
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the 5% NovaMin toothpaste you have to purchase from your dentist
Sensodyne® NUPRO® 5,000 ppm Fluoride Toothpaste with NovaMin®

$67 for a 10 tube case (if you're a dentist)
 
A prescription toothpaste? The price isn't too bad, although who knows what the mark up will be. I'll probably need that though.
 
A successful clinical test study involving a dozen people found that those who rinsed with the UCLA-developed mouthwash just once over a four-day testing period experienced a near-complete elimination of the S. mutans bacteria.

Not much info on the UCLA mouthwash but these are other known ways to eliminate S. mutans bacteria:

Xylitol– a sugar substitute that also kills S. mutans, is already on the market in some toothpaste, mouthwash, & chewing gum products
http://www.xylitol.org

Viruses can target specific bacteria
http://en.wikipedia.org/wiki/Bacteriophage

An oral probiotic is available at all Walgreens in their mouthwash section, called TheraBreath Probiotics. It uses a blend of 2 oral probiotics (K12 + M18) to prevent tooth decay, bad breath, periodontal disease, as well as ear aches – http://www.therabreath.com/probiotics/.
 
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